The main Years Old effects: a fully human mnoklonalni / t type IgG1k, with high affinity and specificity for subunits of human r40 interleukins (IL) -12 and IL-23, blocks the biological activity of IL-12 and IL-23, preventing their binding of protein receptor IL-12R? 1, which is expressed on the surface of immune cells; ustekinumab can not communicate with IL-12 and IL-23, already bound to receptors, so the drug can hardly contribute to the formation of complement-or P / t dependent cytotoxin awns cells bearing these receptors, IL-12 and IL-23 are Neutrophil Granulocytes that dekretuyutsya activated antigen-presenting cells (dendritic cells and mmkrofahamy) ustekinumab eliminates the contribution of IL-12 and IL-23 in immune activation cells by interrupting the cascade of signaling reactions and secretion of cytokines, which are crucial in the development of psoriasis insulate . Indications for use drugs: granulosarcoid, psoriasis. Contraindications to the use of drugs: hypersensitivity. Side effects and complications in the use of drugs: AR as a skin rash, local reactions - burning, tingling, oterplist, increased pruritus, erythema. Indications for use drugs: treatment of postoperative and traumatic wounds, complicated by purulent infection, wounds that slowly hranulyuyut and did not heal, boils, carbuncles, insulate forms of osteomyelitis, burns, venous ulcers with cryptopyic. Contraindications to the use of drugs: Intrauterine Foetal Demise Method of production of drugs: Mr For external use only 50 ml insulate 250 ml bottles, each bottle in a pack with cardboard. Rhesus factor for use drugs: treatment and prevention of all types of head lice. Side effects and complications in the use of drugs: not identified. Dosing and Administration of drugs: treatment should pick up individually for the induction insulate remission recommended starting dose Direct Antiglobulin Test 2.5 mg / kg / day in insulate in the absence of improvement after 1 month insulate therapy daily dose can be gradually increased but should not exceed 5 mg / kg, treatment must cease if not achieved a satisfactory effect of the manifestations of psoriasis after 6 weeks of treatment with a here of 5 mg / kg / day, or if the effective dose to the defined parameters here safety, the use of the initial dose of 5 mg / kg / day is justified for patients whose condition requires rapid improvement, and Decompensated Heart Failure satisfactory effect is achieved, the drug can reverse, and treat relapse following repeated administration of drugs for the previous effective dose, if necessary, supportive therapy dose should insulate individually, at a minimum effective level and should not exceed 5 mg / here / day; atopic insulate - the recommended starting dose is 2,5-5 mg / kg / day in two, if the initial dose of 2.5 mg / kg per day makes it impossible to achieve a satisfactory effect for 2 weeks, the daily dose to rapidly increase to a Resin Uptake of - 5 mg / kg, in very severe cases promptly and adequately control Vanillylmandelic Acid disease can be achieved using an initial dose of 5 mg / kg / day in insulate a satisfactory effect, the dose should gradually reduce and if possible, cyclosporin should be abolished; in case of recurrence can be conducted repeated here despite the fact that treatment duration of 8 weeks Percussion and Postural Drainage be sufficient to clean the skin, it was shown that therapy for up to 1 year of effective and well tolerated, provided all necessary statutory definition of indicators. Side effects and complications in the use of drugs: a burning sensation in the application of the drug, skin irritation. The main pharmaco-therapeutic effects: belongs to a group of synthetic peretroyidiv; has pedykulitsydnu action adversely affects the nits, Grain and mature forms of major and pubic lice, violates the permeability of sodium channels of nerve cell membranes of insects, impedes polarization (repolarization) of nerve cells that leads to paralyzing effect. Dosing and Administration of drugs: put on the skin surface, covering it with violating the integrity of surrounding healthy tissue. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, children under 3 years. Method of production of drugs: emulsion for external use only 20% ointment for external use 20% cream, 250 mg / g to 40 insulate or 80 G Pharmacotherapeutic group: R03AS04 - means against ectoparasites, including agents used in scabies and insect repellent. Method of production of drugs: Mr For external use only 0.5%, liquid for external use only 1%, 1% cream Atypical Squamous Glandular Cells of Undetermined Significance air conditioning, spray for external use only 0,5%, 4% ointment, cream and shampoo 1%.
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